Novel carbacyclins, their preparation and use

Details Novel carbacyclins, their preparation and use Novel carbacyclins, their preparation and use

1985-05-28

1987-11-24

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514573, 514601, 514616, 514623, 546342, 548562, 549 13, 549 79, 549427, 549501, 556437, 560 56, 560116, 560119, 560256, 562466, 562498, 562501, 564 98, 564158, 564159, C07C17700, A61K 31557

Patent

active

047089636

ABSTRACT:
Carbacyclin derivatives of Formula I ##STR1## wherein R.sub.1 is OR.sub.2, wherein R.sub.2 is hydrogen, alkyl, cycloalkyl, aryl, a heterocyclic residue, or NHR.sub.3, wherein R.sub.3 is an acid residue or hydrogen;

REFERENCES:
patent: 4036075 (1981-12-01), Aristoff
patent: 4238414 (1980-12-01), Morton
patent: 4306076 (1981-12-01), Nelson
patent: 4338457 (1982-07-01), Aristoff
patent: 4346041 (1982-08-01), Aristoff
patent: 4349689 (1982-09-01), Aristoff
patent: 4420632 (1983-12-01), Aristoff
patent: 4423067 (1983-12-01), Skuballa et al.
patent: 4497830 (1985-02-01), Skuballa et al.
Burger et al., Medicinal Chemistry, 2nd Edition, 81-82 (1960).
"Annual Reports in Medicinal Chemistry", Academic Press Inc., vol. 21, 1986, p. 283.

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