Novel .beta.-lactam acetic acid derivatives

Details Novel .beta.-lactam acetic acid derivatives Novel .beta.-lactam acetic acid derivatives

1982-03-04

1986-03-18

Berch, Mark L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602452T, C07D20508, C07D48704

Patent

active

045767467

ABSTRACT:
New .beta.-lactam acetic acid derivatives I ##STR1## wherein R represents alkyl, alkyl substituted with amino, protected amino, mono- or di-alkylamino, hydroxy, protected hydroxy or alkoxy, and alkenyl, and their salts are useful as intermediates for preparing 1-azabicyclo [3.2.0]hept-2-ene antibiotics II ##STR2## The process for preparing the .beta.-lactam acetic acid derivatives I as well as the overall process which starting from the acids I leads to the antibiotics II are also claimed.

REFERENCES:
patent: 4269772 (1981-05-01), Melillo
patent: 4282148 (1981-08-01), Liu
patent: 4287123 (1981-09-01), Liu
patent: 4290947 (1981-09-01), Christensen
patent: 4312871 (1982-01-01), Christensen
Kametani et al., J.C.S. Perkins I, 2228 (1981).
Favara et al., Tet. Letters 23, 3105 (1982).
Cama et al. J. Am. Chem. Soc., 100, 8006-7 (1978).
Kametani et al., J. Am. Chem. Soc., 102, 2060-5 (1980).
Ratcliffe et al., Tetrahedron Letters, 21, 31-4 (1980).
Cama et al., Tetrahedron Letters, 21, 2013-6 (1980).
Melillo et al., Tetrahedron Letters, 21, 2783-6 (1980).

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