Novel berbine derivatives

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424258, C07D21520

Patent

active

040339661

ABSTRACT:
Novel berbine derivatives of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are each methoxy or jointly a methylenedioxy, R.sub.3 is methyl, 4-methoxyphenyl or phenylvinyl, and X is a pharmaceutically acceptable anion. They inhibit the growth of transplanted sarcoma strain in mice.

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patent: 3910938 (1975-10-01), Ikekawa et al.
patent: 3920665 (1975-11-01), Shimada et al.
Fukuda et al., Chemical Abstracts 73:86087a, (1970).
Yu et al., Chemical Abstracts 67:82289w, (1967).
Sun et al., Chemical Abstracts 63:7062d, (1965).
Shamma et al., J. Am. Chem. Soc., 92:16, Aug. 12, 1970.

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