Novel bacterium inducible to produce unique steroid-transforming

Details Novel bacterium inducible to produce unique steroid-transforming Novel bacterium inducible to produce unique steroid-transforming

1985-10-23

1989-10-17

Warden, Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving oxidoreductase

435190, 4352521, 435829, C12Q 132, C12N 904, C12R 105

Patent

active

048746967

ABSTRACT:
The present invention discloses a unique biologically pure culture of a microorganism belonging to Alcaligenes species. The microorganism has the property of producing novel 17.beta.-hydroxysteroid dehydrogenase (17.beta.-HSD) capable of enzymatic reaction with an androgen and an estrogen. The methods of isolation the microorganism and the 17.beta.-HSD have been described. An assay and a kit for detecting the presence of C.sub.18 and C.sub.19 steroids in biological samples have also been disclosed.

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