Novel bacteriophage and method for preparing same

Details Novel bacteriophage and method for preparing same Novel bacteriophage and method for preparing same

1978-04-12

1982-06-01

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

435238, 435253, 435235, 435317, C12N 1500

Patent

active

043328970

ABSTRACT:
A novel bacteriophage whose DNA molecule has endonuclease-sensitivity only in the DNA region carrying genetic information for the production of phage coat proteins can be obtained by isolating an endonuclease-resistant mutant from one of the lambdoid bacteriophages and mating the resulting bacteriophage with a lambdoid phage having endonuclease-sensitivity in the DNA region carrying genetic information for the production of coat proteins.

REFERENCES:
patent: 4259444 (1981-03-01), Chakrabarty
Book: Author--Pelczar et al.; Title--Microbiology, Fourth Edition, McGraw-Hill Book Company; pp. 228-232.
Aritcle: Author--Kokisato et al.; Title--Suppressor-Sensitive Mutants of Coliphage .phi.80, Virology 34, (1968), pp. 637-649.
Rambach et al., Proc. Natl. Acad. Sci USA vol. 74 pp. 3927-3930 (Oct. 1974).
Lamanna et al., Basic Bacteriology, It's Biological and Chemical Background, 3rd Ed. pp. 723-727 (1965).
Metzler, Biochemistry, The Chemical Reactions of Living Cells, Academic Press Inc. pp. 945-946 (1977).
Scott et al., Molecular Cloning of Recombinant DNA pp. 133-153 (1977).
Lewin, Gene Expression-3 pp. 269, 270, 879, 886-901 (1977).
Murray et al., Nature vol. 251 pp. 476-481 Oct. 11, 1974.

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