Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1988-02-26
1992-03-24
Kepplinger, Esther L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 732, 435 79, 435 35, 435 36, 435 39, 435810, 435820, 435885, 435 72, 436501, 436518, 436804, 436808, 530415, 530825, 5303895, G01N 33569, G01N 3353, C12Q 114
Patent
active
050988271
ABSTRACT:
The subject invention concerns a novel in vitro process for identifying and quantifying native antigens on potentially pathogenic group B streptococci bacteria present in a clinical specimen. The invention process is made possible by the discovery of novel bacterial markers denoted .gamma. and .delta. epitopes which are expressed by a variety of group B streptococcal strains.
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Brady et al., The Journal of Infectious Diseases, vol. 158 (5), pp. 965-972 (1988).
Jelinkova, J. (1977) "Group B Streptococci in the Human Population," Current Topics in Microbiology and Immunology 76:127-165.
Lim, D. V., W. J. Morales, A. F. Walsh and D. Kazanis (1986) "Reduction of Morbidity and Mortality Rates for Neonatal Group B Streptoccal Disease through Early Diagnosis and Chemoprophylaxis," J. Clin. Micro. 23:489-492.
Boyer, K. M. and S. P. Gotoff (1986) "Prevention of Early-Onset Neonatal Group B Streptococcal Disease with Selective Intrapartum Chemoprophylaxis," New England J. Med. 314:1665-1669.
Russell-Jones, G. J., E. C. Gotschlinch, and M. S. Blake (1984) "A Surface Receptor Specific for Human IgA on Group B Streptococci Possessing the Ibc Protein Antigen," J. Exp. Med. 160:1467-1475.
Russell-Jones, G. J. and E. C. Gotschlich (1984) "Identification of Protein Antigens of Group B Streptococci, with Special Reference to the Ibc Antigens," J. Exp. Med. 160:1476-1484.
Boyle Michael D. P.
Brady L. J.
Kepplinger Esther L.
Scheiner Toni R.
The University of Florida
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