Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1988-04-25
1992-01-14
Teskin, Robin L.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
4352525, 43525231, 4351723, 935 74, 935 56, C12N 112, C12P 2100, A61K 3700
Patent
active
050808974
ABSTRACT:
The present invention relates to novel Bacillus thuringiensis transconjugant strains having improved insecticidal activity. The novel strains are produced by a combination of plasmid curing and conjugation of active strains.
REFERENCES:
patent: 1479279 (1989-01-01), Karamata et al.
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Chapman et al., 1985, "Conjugal Plasmid Transfer in Bacillus Thuringiensis", in Plasmids in Bacteria, Helinski et al., ed., Plenum Publish. Corp. (1985), pp. 453-467.
Carlton et al., 1985, in D. Dubnau, ed., The Molecular Biology of the Bacilli, vol. II, Academic Press (1985), pp. 211-249.
Carlton et al., 1985, "Plasmids and Delta-Endotoxin Production in Different Subspecies of Bacillus thuringiensis", in Molecular Biology of Microbial Differentiation, Hoch, ed., Am. Soc. Microb. (1985) pp. 246-252.
Gonzalez, Jr., 1984, "Genetic Analysis of the Toxin Plasmids of Bacillus Thuringiensis", Ph.D. Thesis, University of Georgia, pp. 112-154.
Gonzalez, Jr. et al., Plasmid (1984) 11:28-38.
Klier et al., Mol. Gen. Genet. (1983) 191:257-262.
Kronstad et al., J. Bacteriol. (1983) 154:419-428.
Ward et al., FEBS Lett. (1983) 158:45-49.
Gonzalez, Jr. et al., Proc. Natl. Acad. Sci. U.S.A. (1982) 79:6951-6955.
Gonzalez et al., 1982, "Plasmid Transfer in Bacillus thurgiensis", in Genetic Exchange, Streips et al., ed., Marcel Dekker, Inc. (1982) pp. 85-95.
Gonzalez et al., Plasmid (1981) 5:351-365.
Minnich et al., "Regulation of Protoxin Synthesis in Bacillus thuringiensis", J. Bacteriol. 158:447-454 (1984).
Gonzalez, Jr. Jose M.
Macaluso Anthony
Ecogen Inc.
Egolf Christopher
Teskin Robin L.
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