Novel azabicyclo octane derivative and process for preparing sam

Details Novel azabicyclo octane derivative and process for preparing sam Novel azabicyclo octane derivative and process for preparing sam

1974-07-10

1976-01-13

Moyer, Donald B.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26032632, 26032643, 2603265B, 2603268, 26032687, 424266, 424274, C07D45102, C07D40106, C07D20902, C07D20932

Patent

active

039324290

ABSTRACT:
A compound of the formula: ##SPC1##
Wherein R.sup.1 is hydrogen, phenyl, alkyl of one to five carbon atoms, cycloalkyl of three to four carbon atoms, or alkyl of one to five carbon atoms having a substituent selected from the group consisting of phenyl, benzoyl and 4-fluorobenzoyl, R.sup.2 is hydrogen or alkyl of one to three carbon atoms, and R.sup.3 is hydrogen, alkanoyl of two to six carbon atoms, benzoyl or nicotinoyl, is disclosed. Several methods for preparing the compound (I) is also disclosed. The compound (I) and a pharmaceutically acceptable acid addition salt thereof are useful as analgesic agents.

REFERENCES:
patent: 3600400 (1971-08-01), Schenker
Chemical Abstracts Vol. 76:14312j (1972).

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