Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1985-07-29
1987-05-26
Fan, Jane T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549264, 435119, C07D49322, A61K 3134
Patent
active
046686967
ABSTRACT:
There is disclosed a macrolide isolated from the fermentation broth, with 22,23-dihydro avermectin Bla aglycone as a substrate, of a known microorganism identified as MA-5853. The structure of the novel compound isolated from the microorganism is presented based upon analytical studies. The compound is a highly potent antiparasitic, insecticidal, and anthelmintic agent. Compositions for such uses are also disclosed.
REFERENCES:
patent: 4199569 (1980-04-01), Chabala et al.
patent: 4206205 (1980-06-01), Mrozik et al.
patent: 4310519 (1982-01-01), Albers-Schonberg et al.
Goegelman Robert T.
Inamine Edward S.
White Raymond F.
Fan Jane T.
Merck & Co. , Inc.
Rose David L.
Sudol, Jr. Michael C.
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