Novel avermectins are produced from known microorganisms

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Process involving micro-organisms of different genera in the...

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435 75, 435 76, 435119, 4352524, 4352536, 435839, 435897, 514 30, 536 71, C12P 1718, C12P 3900, C12P 1960, C12R 1045

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active

050700154

ABSTRACT:
Incubation of 13-deoxy ivermectin aglycone with a species of B. subtilis and of S. griseus results in the production of 13-.beta. ivermectin monoglucopyranoside as the major product and of 5-.beta. ivermectin monoglucopyranoside as the minor product.

REFERENCES:
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patent: 4206205 (1980-06-01), Mrozik et al.
patent: 4310519 (1982-01-01), Albers-Schonberg et al.
patent: 4835141 (1989-05-01), Cullen et al.
patent: 4895837 (1990-01-01), Mrozik et al.

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