Novel arginine vasopressin-binding peptides

Details Novel arginine vasopressin-binding peptides Novel arginine vasopressin-binding peptides

1988-08-19

1990-08-21

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514807, 514869, 530800, A61K 3734

Patent

active

049506501

ABSTRACT:
The invention concerns novel AVP-binding peptides having the formula:

REFERENCES:
patent: 4597901 (1986-07-01), Yim
patent: 4719199 (1988-01-01), Yim
Sawyer, W. H. (1961) "Neurohypophyseal Hormones," Pharmacol. REv. 13:255-277.
Rossi, N. F. and R. W. Schrier (1986) "Role of Arginine Vasopressin in Regulation of Systemic Arterial Pressure," Ann. Rev. Med. 37:13-20.
Gibbs, D. M. (1986) "Vasopressin and Oxytocin: Hypothalamic Modulators of the Stress Response: A Review," Psychoneuroendocrinology 11:131-140.
Doris, P. A. (1984) "Vasopressin and Central Integrative Processes," Neuroendocrinology 38:75-85.
Johnson, H. M. and B. A. Torres (1988) "A Noval Arginine Vasopressin-Binding Peptide That Blocks Arginine Vasopressin Modulation of Immune Function," J. Immunol. 141:2420-2423.
Manning, M. and W. H. Sawyer (1985) "Development of Selective Agonists and Antagonists of Vasopressin and Oxytocin," In: Vasopressin, R. W. Schier (ed.) Raven Press, New York, pp. 131-144.
Johnson, H. M., W. L. Farrar, and B. A. Torres (1982) "Vasopressin Replacement of Interleukin 2 Requirement in Gamma Interferon Production: Lymphokine Acitivity of a Neuroendocrine Hormone," J. Immunol. 129:983.
Johnson, H. M., and B. A. Torres (1985) "Regulation of Lymphokine Production by Arginine Vasopression and Oxytocin: Modulation of Lymphocyte Function by Neurohypophyseal Hormones," J. Immunol. 135:773s.
Stassen, F. L., G. D. Heckman, D. B. Schmidt, J. Stefankiewicz, L. Sulat, W. F. Huffman, M. M. Moore, and L. B. Kinter (1985), "Actions of Vasopressin Antagonists: Molecular Mechanisms," in Vasopressin (ed. R. W. Schrier) pp. 145-154, Raven Press, New York.

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