Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-07-06
1992-02-25
Goldberg:, Jerome
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3135
Patent
active
050914120
ABSTRACT:
Novel terpene hydroquinones have been isolated from the marine sponge Stronglophora hartmanii. These compounds have been found to have antiviral activity. Thus, these compounds, and derivatives thereof, can be used to treat viral infections. Additionally, the subject invention concerns the discovery that the terpene hydroquinone known as aureol has strong antiviral activity.
REFERENCES:
patent: 4548814 (1985-10-01), Rinehart, Jr.
patent: 4731366 (1988-03-01), Munro et al.
patent: 4737510 (1988-02-01), Rinehart, Jr.
patent: 4808590 (1989-02-01), Higa et al.
Faulkner, D. J. (1984) Natural Products Reports 1:551-598.
Faulkner, D. J. (1986) Natural Products Reports 3:1-33.
Faulkner, D. J. (1987) Natural Products Reports 4:539-576.
Uemura, D. K. Takahashi, T. Yamamoto, C. Katayama, J. Tanaka, Y. Okumura, Y. Hirata (1985) "Norhalichondrin A: An Antitumor Polyether Macrolide from a Marine Sponge," J. Am. Chem. Soc. 107:4796-4798.
Djura, P., D. B. Stierle, B. Sullivan, D. J. Faulkner, E. Arnold, J. Clardy (1980) "Some Metabolites of the Marine Sponges" Smenospongia aurea and Smenospongia (.tbd.Polyfibrospongia) echina, J. Org. Chem. 45:1436-1441.
Luribrand, R. T., T. R. Erdman, J. J. Vollmer, P. J. Scheuer, J. Finer, J. Clardy (1979) "Ilimaquinone, a sesquiterpenoid quinone from a marine sponge," Tetrahedron 35:609-612.
Ravi, B. N., H. P. Perzanowski, R. A. Ross, T. R. Erdman, P. J. Sheuer, J. Finer, J. Clardy (1979) "Recent Research in Marine Natural Products: Puupehenones," Pure & Appl. Chem. 51:1893-1900.
Minale, L., R. Riccio, G. Sodano (1974) "Avarol, a Novel Sesquiterpenoid Hydroquinone with a Rearranged Drimane Skeleton from the Sponge Disidea Avara," Tetrahedron Letters 38:3401-3404.
Burres Neal S.
Cross Sue S.
Koehn Frank
Wright Amy S.
Goldberg: Jerome
Harbor Branch Oceanographic Institution Inc.
LandOfFree
Novel antiviral terpene hydroquinones and methods of use does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel antiviral terpene hydroquinones and methods of use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel antiviral terpene hydroquinones and methods of use will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1893274