Novel antimicrobial peptide

Details Novel antimicrobial peptide Novel antimicrobial peptide

1988-05-26

1991-07-16

Moskowitz, Margaret

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530324, C07K 710

Patent

active

050325744

ABSTRACT:
This invention provides a purified polypeptide useful as an antimicrobial agent. This purified polypeptide has been derived from human granulocytes, and has a molecular weight of about 3,700 daltons and the N-terminal amino acid sequence val-cys-ser-cys-arg-leu-val-phe-cys-arg-arg-thr-glu- leu-arg-val-gly-asn-cys-leu-ile-gly-gly-val-ser-phe-thr-try-cys-thr-arg-va l. This invention also provides methods for producing this polypeptide, pharmaceutical compositions containing the polypeptide, and uses thereof.

REFERENCES:
patent: 4705777 (1987-11-01), Lehrer

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