Novel antibacterial amide compounds and process means for produc

Details Novel antibacterial amide compounds and process means for produc Novel antibacterial amide compounds and process means for produc

1974-12-23

1976-05-04

Schwartz, Gerald A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260243C, 424246, 424271, C07D49968, C07D49970, C07D49966

Patent

active

039547345

ABSTRACT:
Novel organic amide compounds which are N-[6-[(substituted amino)phenyl]-1,2-dihydro-2-oxonicotinyl]penicillin and cephalosporin type compounds having broad spectrum antibacterial utility are provided by (a) reacting the free amino acid of the appropriate penicillin or cephalosporin or the acid salt or silylated derivative thereof with a reactive derivative of the corresponding N-6-[(substituted amino)phenyl]-1,2-dihydro-2-oxonicotinic acid or (b) reacting the free amino acid 6-amino-penicillanic acid, 7-aminocephalosporanic acid, 7-amino-3-methylceph-3-em-4-carboxylic acid or a related compound or the acid salt or silylated derivative thereof with a reactive derivative of the corresponding D-N-[6-[(substituted amino)phenyl]-1,2-dihydro-2-oxonicotinyl]-2-substituted glycine. Pharmaceutical compositions containing said compounds and methods for treating infections using said compositions are also disclosed.

REFERENCES:
patent: 3433784 (1969-03-01), Long et al.
patent: 3864329 (1975-02-01), Tobiki et al.

Affiliated with

Also associated with

Rating

Novel antibacterial amide compounds and process means for produc does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel antibacterial amide compounds and process means for produc, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel antibacterial amide compounds and process means for produc will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-678444