Novel anthranilic acid derivatives

Details Novel anthranilic acid derivatives Novel anthranilic acid derivatives

1980-05-21

1982-06-29

Breitenstein, G. T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424230, 424309, 424319, 560 21, 560 45, 560 46, 562435, 562452, 562453, 562455, A61K 31245, C07C10172

Patent

active

043372708

ABSTRACT:
Novel anthranilic acid derivatives of the general formula: ##STR1## wherein X is a halogen atom, an alkoxyl group having 1-3 carbon atoms, an alkyl group having 1-3 carbon atoms or a nitro group, n is an integer of 1-2, Y is an alkoxyl group having 1-3 carbon atoms, m is an integer of 2-3, Z is --COCH.dbd.CH-- or --CO--, R.sub.1 is a hydrogen atom or an alkyl group having 1-4 carbon atoms, and pharmaceutically acceptable salts thereof, which derivatives and salts possess a strong antiallergic action and are thus useful as therapeutically active agents for diseases caused by allergies, such as asthma, hay fever, urticaria and atopic dermatitis; an antiallergic composition comprising the same; and a method of alleviating diseases caused by allergies using the same.

REFERENCES:
patent: 3674844 (1972-07-01), Shen et al.
patent: 3814772 (1974-06-01), Philippe et al.
patent: 3940422 (1976-02-01), Harita et al.
patent: 4026896 (1977-05-01), Harita et al.
Kamijo et al., Chem. Absts., 88, 6568(e) and 6569(f), 1978.
Harita et al., Chem. Absts., 81, 135741(k), 1974.

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