Novel androstane-17.beta.-carboxylic acid esters, a process and

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

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540 70, A61K 3158, C07J 7100

Patent

active

048207004

ABSTRACT:
The invention refers to compounds having anti-inflammatory activity, characterized by the formula ##STR1## in the form of a stereoisomeric mixture or an epimer of the R or S type regarding the orientation of the substituents in the carbon atom at position 20, in which formula the 1,2 position is saturated or is a double bond,

REFERENCES:
patent: 4119625 (1978-10-01), Schmidlin
patent: 4198336 (1980-04-01), Alvarez
patent: 4198403 (1980-04-01), Alvarez
R. Brattsand, A. Thalen, K. Roempke, L. Kallstrom, E. Gruvstad--Influence of 16.alpha.,17.alpha.-Acetal Substitution and Steroid Nucleus Fluorination on the Topical to Systemic Activity Ratio of Glucocorticoids-1982.
R. Brattsand, A. Thalen, K. Roempke, L. Kallstrom, E. Gruvstad--Development of New Glucocorticosteroids with a Very High Ratio Between Topical; and Systemic Activities-1982.

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