Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1976-05-24
1977-05-10
Randolph, John D.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424263, 424270, 2602471M, 260268H, 260295AM, 260301, 2603067R, 2603451, 2603457, 2603473, 2603477, 260468D, 260483, C07D40102, C07D27702
Patent
active
040227944
ABSTRACT:
This invention relates to novel 9-thia-, 9-oxothia-, and 9-dioxothia-11-oxo-12-azaprostanoic acid compounds, salts, and derivatives thereof and also to processes for the preparation of such compounds. These compounds have prostaglandin-like biological activity and are particularly useful as renal vasodilators, as platelet aggregation inhibitors, and for the treatment of certain autoimmune diseases.
REFERENCES:
Ambrus et al, Prostaglandins, vol. 10, pp. 661-666 (Oct. 1975).
Cragoe, Jr. Edward J.
Lee Ta-jyh
Smith Robert L.
Anderson, Jr. Rudolph J.
Arther Thomas E.
Merck & Co. , Inc.
Randolph John D.
Westlake, Jr. Harry E.
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