Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1987-06-11
1990-02-27
Wax, Robert A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
424 44, 4351723, 4352402, 435243, 436501, 536 27, 935 2, 935 4, 935 33, 935 34, 935 36, 935 77, 935 78, C12Q 168, C07H 1512, G01N 33566
Patent
active
049045822
ABSTRACT:
Novel oligonucleotide conjugates are provided, where oligonucleotides are joined through a linking arm to a hydrophobic moiety. The resulting conjugates are more efficient in membrane transport, so as to be capable of crossing the membrane and effectively modulating a transcriptional system. In this way, the compositions can be used in vitro and in vivo, for studying cellular processes, protecting mammalian hosts from pathogens, and the like.
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Rowland Bertram I.
Synthetic Genetics
Wax Robert A.
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