Novel amino-indazole compounds

Details Novel amino-indazole compounds Novel amino-indazole compounds

1974-02-07

1976-06-29

Moyer, Donald B.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260311, 424273, C07D23156, A61K 31415, A01N 922

Patent

active

039667618

ABSTRACT:
This invention provides novel tertiary aminoindazole compounds of the following general formula: ##SPC1##
Wherein R represents a hydrogen or halogen atom; R.sub.1 represents an alkyl group, a substituted or unsubstituted aryl group or a substituted or unsubstituted aralkyl group; R.sub.2 and R.sub.3 both represent a lower alkyl or aralkyl group and W represents a branched chain alkylene group, and salts, especially acid addition and quaternary ammonium salts thereof, and processes for making them. Such compounds are pharmacologically active in that they exhibit antiinflammatory and analgesic effects so the invention also provides pharmaceutical compositions containing one or more of these compounds as the active ingredient. They are also useful anti-microbial agents.

REFERENCES:
patent: 3318905 (1967-05-01), Palazzo
patent: 3767670 (1973-10-01), Podesva et al.
Kataoka et al., Chem. Pharm. Bull. vol. 19, pp. 1511-1513 (1971) (July) RS1.C4.
Palazzo et al., J. Med. Chem. vol. 9, pp. 38-41 (1966) RS1.J5.

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