Novel amino-dioxepane intermediates for the synthesis of new non

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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549347, 564153, A61K 2902, C07C10378

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active

043417566

ABSTRACT:
Novel intermediates for non-ionic polyiodo amino-substituted benzenepolyamides having polyol substituents on the amide nitrogens are provided which are 5-amino-6-hydroxy-1,3-dioxepanes. The compounds provide an economic and efficient route to novel contrast media having excellent chemical and physiological properties.
Also provided are methods for preparing the subject compounds.

REFERENCES:
patent: 4021481 (1977-05-01), Almen et al.
patent: 4239747 (1980-12-01), Pfeiffer et al.

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