Novel amino acid derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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Details

548344, 530331, C07D40100, C07D23364, C07K 508, C07K 506

Patent

active

048701831

ABSTRACT:
Novel amino acid derivatives useful as a therapeutic agent are disclosed. These amino acid derivatives and the pharmaceutically acceptable salts thereof have a human renin inhibitory effect when administered orally and are useful for treatment of hypertension, especially renin-associated hypertension.

REFERENCES:
patent: 4234571 (1980-11-01), Nestor et al.
patent: 4548926 (1985-10-01), Matsueda et al.
patent: 4591648 (1986-05-01), Jones et al.
patent: 4595677 (1986-06-01), Riniker et al.
patent: 4656269 (1987-04-01), Iizuka et al.
patent: 4666888 (1987-05-01), Raddatz et al.
patent: 4698329 (1987-05-01), Matsueda et al.
patent: 4711958 (1987-12-01), Iizuka et al.
patent: 4814342 (1989-03-01), Hoover et al.
Kobuku et al., "Highly Potent and Specific Inhibitors, Etc.," Biochemical and Biophysical Research Comm., vol. 118, No. 3, pp. 929-933 (2-1984).
106th Annual Meeting of Pharmaceutical Society of Japan (Apr. 1986)-Iizuka et al. presentation.
The 50th Annual Meeting of the Japanese Circulation Society (Mar. 1986)-Aoi et al., Abstract followed by presentation.
50th Annual Meeting of the Japanese Circulation Society (Mar. 1986) Miyazaki et al., abstr.
59th (general Meeting of the Japanese Pharmacological Society (Apr. 1986) Miyazaki et al., abstr. & presentation.
Brown et al., "Protection of histidine side-chains, etc." Chemical Abstracts 95:220299f (1981).
Colombo et al., "Acid-labile histidine side-chain protection," Chemical Abstracts 101:23914n (1984).
The Abstract of Miyazaki et al., presentation of the 9th Japanese Society of Hypertension.
The Abstract of the 8th Seminar of Antihypertension Drugs held on Apr. 2, 1987.
The Abstract of the American Society of Hypertension (ASH) World Biologically Active Artial Peptides (BAAP).
Abstract of Kubota et al., presentation at the 37th Regional Meeting of Japanese Pharmocological Society.
European Journal of Pharmacology vol. 129, No. 3, pp. 393-396, Toda et al. entitled "Human Renin Inhibiting dipeptide," 1986.

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