Novel alkyl substituted fluorescent compounds and polyamino acid

Details Novel alkyl substituted fluorescent compounds and polyamino acid Novel alkyl substituted fluorescent compounds and polyamino acid

1979-09-07

1982-09-28

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

23230B, 260112B, 2601125R, 2601127, 260121, 424 8, 424 12, 424 85, 424 88, 435 7, 435188, 525420, 549388, A61K 39385, A61K 3944, C07G 700

Patent

active

043517609

ABSTRACT:
Fluorescent antigen conjugates are provided comprising antigens covalently bonded to at least one 2,7-dialiphatic substituted-9-phenyl-6-hydroxy-3H-xanthen-3-one, wherein the 1- and 8-positions are unsubstituted. Also provided are novel fluorescent compounds absorbing at wavelengths in excess of 500 nm, having active functionalities for linking to the antigen. Finally, methods are provided for analyzing antigens in serum, whereby serum interference is avoided.

REFERENCES:
patent: 4174384 (1979-11-01), Ullman et al.
patent: 4193983 (1980-03-01), Ullman et al.
patent: 4220450 (1980-09-01), Maggio
patent: 4230805 (1980-10-01), Singh et al.
patent: 4318846 (1982-03-01), Khanna et al.

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