Novel 8-(lower alkyl)bicyclo[4.2.0]octane derivatives with valua

Details Novel 8-(lower alkyl)bicyclo[4.2.0]octane derivatives with valua Novel 8-(lower alkyl)bicyclo[4.2.0]octane derivatives with valua

1986-07-28

1987-07-07

Lone, Werren B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514511, 514703, 514729, 514557, 560119, C07C 6974

Patent

active

046788050

ABSTRACT:
Compounds useful in treating cardiovascular disorders such as thrombosis, hypertension, and atherosclerosis are compounds depicted in formulas (1), (2), and (3): ##STR1## wherein: Y is exo-(lower alkyl) or endo-(lower alkyl);

REFERENCES:
patent: 4306076 (1981-12-01), Nelson
patent: 4608388 (1986-08-01), Kluge et al.
Morton et al, "J. Organic Chem.", vol. 44 (1979) p. 2880.
Aristoff et al, "J. Organic Chem.", vol. 48 (1983) p. 5341.
Crossley, "Tetrahedron Letters" (1971) p. 3327.
Corey et al., "Tetrahedron Letters" (1973) p. 3091.
Kojima et al, "Tetrahedron Letters" (1978) p. 3743.
Shibasaki et al "Tetrahedron Letters" (1979) p. 433.

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