Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-07-02
1991-12-31
Shen, Cecilia
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546 68, A61K 3148, C07D45712
Patent
active
050772988
ABSTRACT:
Compounds of formula I ##STR1## wherein R.sub.1 is hydrogen or C.sub.1-4 alkyl, R.sub.2 is hydrogen, chlorine, bromine or methyl, R.sub.3 is C.sub.1-5 alkyl or C.sub.3-5 alkenyl and R.sub.4 is C.sub.3-7 alkyl; C.sub.3-7 cycloalkyl; adamantyl; or optionally substituted phenyl, having valuable pharmaceutical, and in particular LH- and PRL-secretion inhibiting as well as neuroleptic activity.
REFERENCES:
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patent: 3218323 (1965-11-01), Hofmann et al.
patent: 4348391 (1982-09-01), Stutz
patent: 4348392 (1982-09-01), Fehr et al.
patent: 4791115 (1988-12-01), Haefliger
patent: 4950672 (1990-08-01), Haefliger
Honor Robert S.
McGovern Thomas O.
Sandoz Ltd.
Sharkin Gerald D.
Shen Cecilia
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