Novel 6.alpha.-methylprednisolone derivatives, their preparation

Details Novel 6.alpha.-methylprednisolone derivatives, their preparation Novel 6.alpha.-methylprednisolone derivatives, their preparation

1983-10-27

1986-05-06

Roberts, Elbert L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

26039745, 26023955D, A61K 3156

Patent

active

045872368

ABSTRACT:
6.alpha.-Methylprednisolone derivatives of Formula I ##STR1## wherein R.sub.1 is 1-oxoalkyl of 2-6 carbon atoms or benzoyl and

REFERENCES:
patent: 2867632 (1959-01-01), Lincoln, Jr. et al.
patent: 2897218 (1959-07-01), Sebek et al.
patent: 3053832 (1962-09-01), Gould
patent: 3312590 (1967-04-01), Elks et al.
patent: 3422193 (1969-01-01), Shapiro
patent: 4290962 (1981-09-01), Tachi et al.
J. Amer. Chem. Soc., 78, 1956, 6213.
J. Amer. Chem. Soc., 81, 1959, 1235.
European Search Report, dated Nov. 3, 1982, No. EP 82 10 7368.
Apendice ao "Diario da Republica", pp. 1643, 2082-2083.
Anlage F--Pharmakologische Tests, 4 pages (German language).
Enclosure F--Pharmacological Tests, 4 pages (English language).
Early Disclosure Patent Gazette, No. 81-86119, Jul. 13, 1981, 11 pages.

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