Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1978-11-13
1979-12-04
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
260571, A61K 31135, C07C 9116, C07C 9128, C07C 9140
Patent
active
041772920
ABSTRACT:
Novel 5H-benzocyclohepten-7-amines of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of hydrogen and methyl, R.sub.2 and R.sub.3 are individually selected from the group consisting of hydrogen, fluorine, chlorine, bromine, nitro, amino, --CF.sub.3 and methoxy, X is selected from the group consisting of hydrogen and halogen, and their non-toxic, pharmaceutically acceptable acid addition salts having remarkable in vivo and in vitro inhibiting properties for the capture of serotonine and their preparation.
REFERENCES:
patent: 3651143 (1922-03-01), Galantay
patent: 4091115 (1978-05-01), Nedelec et al.
Chem. Abst. 68 87060(v) (1968)--Khanna et al.
Dumont Claude
Frechet Daniel
Hunt Peter
Nedelec Lucien
Robinson Douglas W.
Roussel Uclaf
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