Novel 4-cyanophenyl derivatives with action against cardiac arrh

Details Novel 4-cyanophenyl derivatives with action against cardiac arrh Novel 4-cyanophenyl derivatives with action against cardiac arrh

1988-12-22

1991-07-23

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514524, 558413, 558415, 558422, A61K 31275, C07C25550

Patent

active

050344110

ABSTRACT:
This application relates to novel 4 cyanophenyl derivatives which are useful for the treatment of cardiac arrhythmia and pharmaceutical compositions containing these compounds as the active ingredients.

REFERENCES:
patent: 4544654 (1985-10-01), Davey et al.
Morrison et al., "Organic Chemistry", (1959), p. 553, Allyn and Bacon, Inc., Boston.
Williams, "Classification of Anti-Arrythmic Drugs"; pp. 449-472.
Foye, "Principles of Medicinal Chemistry", 2nd ed., (1981), Lea & Febiger, Philadelphia, pp. 384-385.
Weng et al., "Antiarrhythmic Drugs: Electrophysiological Basis of Their Clinical Usage", pp. 106-112 (1986).

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