Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1981-05-11
1983-06-14
Bond, Robert T.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
2602393D, A61K 3155, C07D24324
Patent
active
043883133
ABSTRACT:
The disclosure is directed to new 3-hydroxy-1,4-benzodiazepine-2-ones and to the process for the preparation thereof. The compounds of the invention have the structural formula ##STR1## in which R is methoxy or nitrile, R.sub.1 is hydrogen, halogen, trifluoromethyl or nitro and R.sub.2 is hydrogen or halogen, with the proviso that R is different from methoxy, if R.sub.2 is o-halogen. The compounds have marked sedative and sleep prolonging activity when evaluated in standard pharmacological procedures.
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Bond Robert T.
Gerot-Pharmazeutika Gesellschaft m.b.H.
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