Novel 3,4-diaza-bicyclo[4.1.0]hept-2-en-5-ones, their preparatio

Details Novel 3,4-diaza-bicyclo[4.1.0]hept-2-en-5-ones, their preparatio Novel 3,4-diaza-bicyclo[4.1.0]hept-2-en-5-ones, their preparatio

1979-11-30

1981-06-02

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544235, 562460, C07D23726, A61K 3150

Patent

active

042711630

ABSTRACT:
2-Aryl-3,4-diaza-bicyclo-[4.1.0]hept-2-en-5-ones, substituted in the phenyl ring, of the general formula ##STR1## their preparation, and therapeutic agents, containing these compounds, which may be used for the treatment of hypertension or of thrombo-embolic disorders.

REFERENCES:
patent: 3689652 (1972-09-01), Curran
patent: 3746712 (1973-07-01), Ross
patent: 3812256 (1974-05-01), Curran
patent: 3822260 (1974-07-01), Curran
patent: 3951176 (1976-01-01), Houlihan
patent: 3975388 (1976-08-01), Hakim
patent: 4088762 (1978-05-01), Hakim
Tetrahedron 30, 501 (1974), Koenig et al.
Maier et al., Chem. Berichte 98, 1965, p. 2438, (1965).
Wermuth et al., Chim. Ther. 6, 109, (1971).

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