Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Peptides containing saccharide radicals – e.g. – bleomycins – etc.
Patent
1984-06-21
1989-02-28
Brown, Johnnie R.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Peptides containing saccharide radicals, e.g., bleomycins, etc.
536 168, C07C10352
Patent
active
048087033
ABSTRACT:
Disclosed is a 3-(4'-aminobutylamino) propylaminobleomycin having low pulmonary toxicity, which expressed by the following general formula
REFERENCES:
patent: Re30451 (1980-12-01), Umezawa et al.
patent: 3922262 (1975-11-01), Umezawa et al.
Umezawa et al., The Journal of Antibiotics, Ser. A, 1966, pp. 200-209, 210-215, published in Japan.
Migrdichian, Organic Synthesis, vol. 1, 1957, p. 472 (published by Reinhol Publ. Corp.).
Fujii Akio
Fukuoka Takeyo
Muraoka Yasuhiko
Nakatani Tokuji
Takahashi Katsutoshi
Brown Johnnie R.
Nields Henry C.
Peselev Elli
Zaidan Hojin Biseibutsu Kagaku Kenku Kai
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