Novel 23-dihydro-oxazolyl steroids

Details Novel 23-dihydro-oxazolyl steroids Novel 23-dihydro-oxazolyl steroids

1985-10-16

1987-08-25

Schenkman, Leonard

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07J 1700

Patent

active

046894101

ABSTRACT:
Novel 23-dihydro-oxazolyl steroids of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of hydrogen and methyl, R.sub.2 is selected from the group consisting of methyl and ethyl, R.sub.3 and R.sub.4 are individually selected from the group consisting of hydrogen and alkyl of 1 to 4 carbon atoms, the A, B, C and D rings may contain 1 to 3 double bonds and may be optionally substituted with one or more members of the group consisting of --OH, protected hydroxyl, .dbd.0, protected keto, halogen alkyl or alkoxy of 1 to 4 carbon atoms and alkenyl and alkynyl of 2 to 4 carbon atoms and the dotted line indicates the optional presence of a second bond useful for the preparation of 20-keto-pregnanes and novel intermediates.

REFERENCES:
patent: 4401596 (1983-08-01), Barton et al.
patent: 4434080 (1984-02-01), Barton et al.
patent: 4460509 (1984-07-01), Mosbach et al.

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