Novel 2-propanol derivatives and preparation thereof

Details Novel 2-propanol derivatives and preparation thereof Novel 2-propanol derivatives and preparation thereof

1973-06-18

1976-04-20

Gallagher, R. J.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260268PH, 26029382, 26029383, 424267, C07D21152

Patent

active

039519864

ABSTRACT:
2-Propanol derivatives of the formula: ##SPC1##
And their pharmaceutically acceptable acid addition salts, which are useful as medicaments and can be produced by reacting a compound of the formula: A-CH.sub.2 -Z with a compound of the formula: A'-H [wherein R is hydrogen or lower alkanoyl; R.sub.1 is hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl; W is oxygen, sulfur, sulfinyl or sulfonyl; Y is a group of either one of the formulae: ##SPC2##
(wherein R.sub.2 is hydrogen, halogen, lower alkyl or lower alkoxy and R.sub.3 is hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl); A and A' are each a group of either one of the formulae: ##SPC3##
(wherein R.sub.1, W and Y are each as defined above), provided that A and A' are different each other; and Z is a group of either one of the formulae: ##EQU1## (wherein X is halogen, alkylsulfonyloxy or arylsulfonyloxy and R is as defined above)].

REFERENCES:
patent: 2960507 (1960-11-01), Stern et al.
patent: 2978454 (1961-04-01), Elpern
patent: 3158616 (1964-11-01), Adickes et al.
patent: 3462444 (1969-08-01), Beckett et al.
patent: 3840529 (1974-10-01), Maruyama et al.
patent: 3845057 (1974-10-01), Maruyama et al.

Affiliated with

Also associated with

Rating

Novel 2-propanol derivatives and preparation thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel 2-propanol derivatives and preparation thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel 2-propanol derivatives and preparation thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1587295