Novel 17-spirosultines

Details Novel 17-spirosultines Novel 17-spirosultines

1977-10-20

1979-05-15

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26023955R, 26023955C, 26039745, 424241, C07J 1700, C07J 3100

Patent

active

041547306

ABSTRACT:
Novel 17-spirosultines of steroids and the corresponding .gamma.-hydroxy acids of the formula ##STR1## wherein R.sub.1 is alkyl of 1 to 4 carbon atoms, A is hydrogen and B is hydrogen or hydroxyl of .beta.configuration or A and B together form a double bond, X and Y together form the group ##STR2## or X is --OH and Y is ##STR3## and M is selected from the group consisting of hydrogen, --NH.sub.4 and an alkali metal having a remarkable progestomimetic and antialdosteronic activity and a novel process for their preparation and novel intermediates.

REFERENCES:
patent: 3576828 (1971-04-01), Anner et al.
patent: 3971777 (1976-07-01), Rousseau et al.

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