Novel 11-desoxy-prostaglandin F.sub.2 derivatives

Details Novel 11-desoxy-prostaglandin F.sub.2 derivatives Novel 11-desoxy-prostaglandin F.sub.2 derivatives

1977-05-02

1978-10-10

Seigel, A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Allergen or component thereof

2603322A, A01N 900, C07D33324

Patent

active

041197275

ABSTRACT:
Novel 11-desoxy-prostaglandin F.sub.2 derivatives of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms, an alkali metal, an equivalent of an alkaline earth metal, magnesium or organic amine base, R.sub.1 and R.sub.2 are individually seleced from the group consisting of hydrogen and methyl and X is selected from the group consisting of ##STR2## and a 5 to 6 membered heterocycle optionally substituted with at least one member of the group consisting of halogen, --CN and alkyl of 1 to 5 carbon atoms and X.sup.1 is a 6 member heterocycle with the wavy lines indicating that the hydroxy may be in either one of the two possible .alpha. and .beta. positions having hypotensive activity and process for their preparation.

REFERENCES:
patent: 3776940 (1973-12-01), Just
patent: 3794664 (1974-02-01), Just
patent: 3956284 (1976-05-01), Hess

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