Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 9,10-seco- cyclopentanohydrophenanthrene ring system doai
Patent
1989-03-09
1990-11-27
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
9,10-seco- cyclopentanohydrophenanthrene ring system doai
552653, 552544, A61K 3159, C07J 1500, C07J 900
Patent
active
049735845
ABSTRACT:
The invention provides a new vitamin D.sub.2 compound, 1.alpha.-hydroxy-24-epi-vitamin D.sub.2 and certain hydroxy-protected derivatives thereof. The new compound exhibits a distinctive activity pattern comprising high potency in stimulating intestinal calcium transport and little or no activity in inducing bone calcium mobilization or the differentiation of undifferentiated cells in culture, thereby evincing utility in the treatment of diseases characterized by loss of bone mass.
REFERENCES:
patent: 3880894 (1975-04-01), DeLuca et al.
patent: 3907843 (1975-09-01), DeLuca et al.
patent: 4588528 (1986-05-01), DeLuca et al.
patent: 4612308 (1986-09-01), Baggiolini et al.
patent: 4717721 (1988-01-01), DeLuca et al.
patent: 4769181 (1988-09-01), DeLuca et al.
DeLuca Hector F.
Perlman Kato L.
Schnoes Heinrich K.
Shah Mukund J.
Ward E. C.
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