Nor-bile acid derivatives, processes for their preparation and t

Details Nor-bile acid derivatives, processes for their preparation and t Nor-bile acid derivatives, processes for their preparation and t

1994-05-05

1996-04-30

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

552509, 514179, A61K 3156, C07J 5300

Patent

active

055125581

ABSTRACT:
nor-Bile acid derivatives, processes for their preparation and the use of these compounds as medicaments nor-Bile acid derivatives of the formula I

REFERENCES:
patent: 4104285 (1978-08-01), Gallo-Torres et al.
patent: 5250524 (1993-10-01), Kramer et al.
Chemical Abstracts, vol. 113, No. 19, Nov. 5, 1990, Abstract No. 172419, "Synthesis of a new molecular receptor based on cholic acid".
Chemical Abstracts, vol. 116, No. 11, 1992, Abstract No. 103302, "Hepatic and ileal transport and effect on biliary secretion of norursocholic acid and its conjugates in rats".
Chemical Abstracts, vol. 103, No. 17, 1985, Abstract No. 134429, "Intestinal Absorption and Metabolism of Norcholic Acid in Rats".
Journal Of Medicinal Chemistry, G. Wess et al., "Specific Inhibitors of Ileal Bile Acid Transport.", vol. 37, No. 7, Apr. 1, 1994.
"Synthesis of 24-nor-5.beta.-cholan-23-oic acid derivatives: a convenient and efficient one-carbon degradation of the side chain of natural bile acids", Schteingart et al., Journal of Lipid Research, 29:1387-1395 (1988) .

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