Nonthrombogenic implant surfaces

Details Nonthrombogenic implant surfaces Nonthrombogenic implant surfaces

1994-06-06

1998-04-21

Mullis, Jeffrey

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

525937, 527300, 527312, C08G 8100

Patent

active

057418527

ABSTRACT:
Triblock polymers comprised of polysaccharide, such as heparin or dextran, and a hydrocarbon chain, have been prepared. The triblock polymer adsorbs strongly on the surface of hydrophobic polymer substrates such as polyethylene, through hydrophobic interaction between the polymer and the hydrophobic hydrocarbon chain of the triblock polymer. The surface adsorbed with triblock polymer is resistant to protein deposition, which renders the surface nonthrombogenic.

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