Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...
Patent
1982-07-13
1985-07-23
Schofer, Joseph L.
Synthetic resins or natural rubbers -- part of the class 520 ser
Synthetic resins
Mixing of two or more solid polymers; mixing of solid...
523112, 5253292, 525123, 525165, 525178, C08G 6946, C08G 6370, C08G 7882, C08F 802
Patent
active
045309744
ABSTRACT:
Articles having reduced thrombogenicity when in contact with blood products containing albumin and methods of their use are provided. The articles comprise at the surface of blood contact a water insoluble polymeric substrate material having covalently attached thereon aliphatic extensions of 14 to 20 carbon units. When exposed to blood the aliphatic chain extensions provide a hydrophobic binding site for albumin. The articles when implemented with whole blood or blood products selectively enhance albumin affinity binding to the exclusion of other blood components, and subsequently minimize thrombus formation.
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Eberhart Robert C.
Ellsworth Steven R.
Munro Mark S.
Quattrone Alfred J.
Board of Regents , The University of Texas System
Kulkosky Peter F.
Schofer Joseph L.
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