Nonpeptidyl platelet aggregation inhibitors having specificity f

Details Nonpeptidyl platelet aggregation inhibitors having specificity f Nonpeptidyl platelet aggregation inhibitors having specificity f

1992-04-10

1993-10-05

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540495, 540512, 540523, C07D26114, A61K 3155

Patent

active

052506797

ABSTRACT:
A benzodiazepinedione derivative which acts as a nonpeptidyl platelet aggregation inhibitor is provided. This inhibitor potently inhibits fibrinogen binding to the GPII.sub.b III.sub.a receptor and is provided in therapeutic compositions for the treatment of diseases for which blocking platelet aggregation is indicated. These nonpeptidyl inhibitors are provided in combination with thrombolytics and anticoagulants.

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