Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1993-02-19
1996-04-23
Tucker, Philip
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514620, 564197, 564198, A61K 3116, C07C10330
Patent
active
055103804
ABSTRACT:
Disclosed are nonpeptides having bradykinin antagonist activity of the formulae (I) and (II) ##STR1## or a pharmaceutically acceptable salt thereof, pharmaceutical compositions containing the compound and methods of treating diseased or pathological conditions using the pharmaceutical compositions.
REFERENCES:
patent: 3935266 (1976-01-01), Hashimoto et al.
patent: 4242329 (1980-12-01), Claeson et al.
patent: 4332822 (1982-06-01), Ward
patent: 4602041 (1986-07-01), Newsome et al.
patent: 4801613 (1989-01-01), Stewart et al.
CA 75:20936m "Guanidines", from Nowak, Kornel (Akad. Med., Wroclan, Pol.) Rocz. Chem., 44 (10) 1905-10 (Pol.) 1970.
Awad Mohamed M. A.
Dolle Roland E.
Douty Brent D.
Faunce David M.
Houck Wayne T.
Balogh Imre (Jim)
Davis William J.
DuPont Paul E.
Kilby Scalzo Catherine
Sterling Winthrop Inc.
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