Nonpeptide bradykinin antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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514620, 564197, 564198, A61K 3116, C07C10330

Patent

active

055103804

ABSTRACT:
Disclosed are nonpeptides having bradykinin antagonist activity of the formulae (I) and (II) ##STR1## or a pharmaceutically acceptable salt thereof, pharmaceutical compositions containing the compound and methods of treating diseased or pathological conditions using the pharmaceutical compositions.

REFERENCES:
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patent: 4242329 (1980-12-01), Claeson et al.
patent: 4332822 (1982-06-01), Ward
patent: 4602041 (1986-07-01), Newsome et al.
patent: 4801613 (1989-01-01), Stewart et al.
CA 75:20936m "Guanidines", from Nowak, Kornel (Akad. Med., Wroclan, Pol.) Rocz. Chem., 44 (10) 1905-10 (Pol.) 1970.

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