Nonionic X-ray contrast agents, compositions and methods

Details Nonionic X-ray contrast agents, compositions and methods Nonionic X-ray contrast agents, compositions and methods

1989-12-13

1991-12-24

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

424 5, A61K 4904, C07H 300, C07C10378

Patent

active

050755021

ABSTRACT:
Triiodinated isophthalamide derivatives, useful as X-ray contrast agents, having at least one amide group derived from the amino-alcohol, 3-(N-2-hydroxyethyl)amino-1,2-propanediol, which provides high water solubility and low mammalian toxicity, and methods of preparing them. Methods of preparing 3-(N-2-hydroxyethyl)amino-1,2-propanediol are provided.

REFERENCES:
patent: 4001323 (1977-01-01), Felder et al.
patent: 4021481 (1977-05-01), Almen et al.
patent: 4239747 (1980-12-01), Pfeiffer et al.
patent: 4352788 (1982-10-01), Felder et al.
patent: 4364921 (1982-12-01), Speck et al.
Speck et al., Chem. Abstracts, vol. 111, No. 15; 133794u (1989).
Felder et al., Chem. Abstracts, vol. 110, No. 21; 192447k (1989).
Pfeiffer et al., Chem. Abstracts, vol. 97, No. 17; 144596z (1982).
Haanaldsen et al., Chem. Abstracts, vol. 100, No. 1; 6000e (1984).
Simo et al., Chem. Abstracts, vol. 102, No. 1; 5958c (1985).
Sovak et al., Chem. Abstracts, vol. 108, No. 10; 82096w (1988).

Affiliated with

Also associated with

Rating

Nonionic X-ray contrast agents, compositions and methods does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nonionic X-ray contrast agents, compositions and methods, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nonionic X-ray contrast agents, compositions and methods will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-44899