Noninvasive and in-vitro measurement of glucose and cholesterol

Details Noninvasive and in-vitro measurement of glucose and cholesterol Noninvasive and in-vitro measurement of glucose and cholesterol

1995-03-10

1997-11-11

Smith, Ruth S.

Surgery

Truss

Pad

1286532, 436 71, 436 74, 436 95, 436173, A61B 50555

Patent

active

056853009

ABSTRACT:
A method of noninvasive and in-vitro glucose and cholesterol concentration measurement employing nuclear magnetic resonance (NMR) spectroscopy is described. The measurement comprises a ratio formed by dividing the area of the resonance of the desired analyte, e.g., glucose or cholesterol, by the area of the water resonance in a spectrum of blood or tissue. In the in-vivo setting, the spectrum is obtained either in linkage with the pulsation of blood or by using a slice selection gradient such as that employed in the magnetic resonance imager. This measurement is then correlated to a traditional serum analyte concentration.

REFERENCES:
patent: 4878021 (1989-10-01), Granot
patent: 4915111 (1990-04-01), Sano et al.
patent: 5072732 (1991-12-01), Rapoport et al.
patent: 5261405 (1993-11-01), Fossel

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