Nonapeptides that bind a HLA-A2.1 molecule

Details Nonapeptides that bind a HLA-A2.1 molecule Nonapeptides that bind a HLA-A2.1 molecule

1996-05-10

2000-10-31

Feisee, Lila

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

530328, A61K 3800, A61K 3804

Patent

active

061404640

ABSTRACT:
The invention described methods for identifying a molecule of interest, as well as nucleic acid molecules which encode it, and binding partners for it. A cDNA library from a cell expressing the target is prepared, and expressed in host cells. Lysates of the host cells are screened with a sample, treated to remove interfering binding partners. The treatment involves contact of the sample to lysates of untransfected host cells, and host cells transfected or transformed with the same vector used to make the cDNA library. Also a part of the invention are antigens and cDNA identified using the methodology.

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