Non-traumatic model for neurogenic pain

Multicellular living organisms and unmodified parts thereof and – Nonhuman animal – The nonhuman animal is a model for human disease

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C800S008000, C514S021800

Reexamination Certificate

active

07015371

ABSTRACT:
Methods for producing nondestructive nerve alterations and/or compressions in animals are provided. The animals provide a model of persistent neurogenic and neuropathic pain in humans. Also provided is a method for screening agents for activity in the treatment of persistent neuropathic pain, as well as methods for use in developing agents for treatment of neuropathic pain. Also provided are methods for detecting and monitoring physiologic changes in persistent pain.

REFERENCES:
Wang, L.X. 2003, Animal and cellular models of chronic pain. Adv. Drug Deliv. Rev. vol. 55, pp. 949-965.
Petersen, K.L. 2001, Effect of remifentanil on pain and secondary hyperalgesis associated with the heat-capsaicin sinsitization model in healthy volunteers, Anesthesiology, vol. 94, pp. 15-20.
Lublin, J. 1998, Carpal tunnel syndrome: a review of initial diagnosis and treatment for the OB/GYN, Prim Care Update Ob/Gyns, vol. 5, pp. 280-285.
Eliav, E., 1999, Neuropathic pain from an experimental neuritis of the rat sciatic nerve, Pain, vol. 83, pp. 169-182.
Keeton, W and Gould, J., Biological Science, 4th edition, W.W. Norton and Company, paragraph bridging pp. 458-459.
Lundborg, G. 1982, Median nerve compression in the carpal tunnel-Functional reesponse to experimentally induced controlled pressure, Journal of Hand Surgery, vol. 1, pp. 252-259.
Wall, 1996, Theriogenology, vol. 45, pp. 57-68.
Houdebine, 1994, J. Biotech. vol. 34, pp. 269-287.
Reyna, 1999, ICLAS, Palma de Malloren, May 26-28, p. 226.
Ford, 1986, Laryngoscope, vol. 96, pp. 1248-1257.
Allodynia, Stedman's Medical Dictionary, http://216.251.232.159/semdweb/internetsomd/ASP/1526727.asp.
Hyperalgesia, Stedman's Medical Dictionary, http://216.251.232.159/semdweb/internetsomd/ASP/1526727.asp.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Non-traumatic model for neurogenic pain does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Non-traumatic model for neurogenic pain, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Non-traumatic model for neurogenic pain will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3550300

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.