Non-toxic biofilm inhibitor

Details Non-toxic biofilm inhibitor Non-toxic biofilm inhibitor

2011-07-12

2011-07-12

Swartz, Rodney P. (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C424S184100, C424S185100, C424S234100, C530S300000, C530S350000

Reexamination Certificate

active

07976851

ABSTRACT:
The present invention relates to a composition and method for preventing or inhibiting biofilm formation on biotic or abiotic surfaces. The composition comprises a peptide based on the C-terminal receptor binding domain ofPseudomonas aeruginosatype IV pilin, which binds to an abiotic surface (e.g., steel, plastic) with high affinity and prevents binding of a variety ofP. aeruginosastrains to the surface. The inventive composition represents a non-toxic inhibitor for biofilm formation, particularly on an abiotic surface, which is responsible for a large number of problematic diseases and massive economic losses. The inventive method is useful as a safe and environmentally friendly means of modifying a surface of a variety of biomedical, nanotechnological, and biotechnological devices or articles.

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