Non-thrombogenic articles

Details Non-thrombogenic articles Non-thrombogenic articles

1977-01-31

1978-09-26

Michl, Paul R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

3 1, 260 9, 424 83, C08L 510

Patent

active

041168984

ABSTRACT:
The disclosure is of articles having reduced thrombogenicity and which are useful for purposes requiring their contact with whole blood. The articles comprise solid, polymeric resin substrates to which there is fixed a compound of the formula: ##STR1## wherein A represents the residue of sodium heparin after removal of the sodium ion. The articles advantageously exhibit low toxicity and excellent blood compatibility when used for purposes which bring them into contact with whole blood for prolonged periods of time.

REFERENCES:
patent: 3457098 (1969-07-01), Leininger
patent: 3514438 (1970-05-01), Bixler
patent: 3585647 (1971-06-01), Gajewski
patent: 3616935 (1971-11-01), Love
patent: 3617344 (1971-11-01), Leininger
patent: 3634123 (1972-01-01), Eriksson
patent: 3673612 (1972-07-01), Merrill
patent: 3755218 (1973-08-01), Yen
patent: 3766104 (1973-10-01), Bonin
patent: 3844989 (1974-10-01), Harumiya
patent: 3846353 (1974-11-01), Grotta

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