Drug – bio-affecting and body treating compositions – Designated organic nonactive ingredient containing other... – Aftertreated solid synthetic organic polymer
Reexamination Certificate
2006-04-25
2006-04-25
Lipman, Bernard (Department: 1713)
Drug, bio-affecting and body treating compositions
Designated organic nonactive ingredient containing other...
Aftertreated solid synthetic organic polymer
C514S002600, C514S056000, C526S286000, C526S287000, C526S320000, C526S333000, C424S078180, C424S078310, C424S078350, C424S078370
Reexamination Certificate
active
07034061
ABSTRACT:
Polymers having non-thrombogenic properties can be prepared by copolymerizing monomers of at least three classes selected from (a) monomers having sulphate groups, (b) monomers having sulphonate groups, (c) monomers having sulphamate groups, (d) monomers having polyoxyalkylene ether groups, and (e) monomers having zwitterionic groups. The polymers can additionally be provided with anti-thrombogenic properties by including an additional comonomer having a pendant heparin (or hirudin, warfarin or hyaluronic acid) group. The polymers can be used as coating materials for medical devices, such as tubing or connectors, in order to provide them with non-thrombogenic, and optionally anti-thrombogenic, properties.
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Heparin Derivatives of High Molecular Weight,by Mester, Amaya and Mester.Carbohydrate Sulfates, (1978) 113-120.
Luthra Ajay Kumar
Sandhu Shivpal Singh
Lipman Bernard
Thompson & Coburn LLP
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