Non-symmetric tripyrranes in the synthesis of novel macrocycles

Details Non-symmetric tripyrranes in the synthesis of novel macrocycles Non-symmetric tripyrranes in the synthesis of novel macrocycles

2006-09-26

2006-09-26

Wilson, James O. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C540S465000, C540S472000, C536S017100, C536S017300, C536S017400, C534S015000

Reexamination Certificate

active

07112671

ABSTRACT:
The present invention provides certain non-symmetric tripyrranes; that is, tripyrranes that do not contain a mirror plane of symmetry perpendicular to the plane containing the tripyrrane. Further, the invention includes texaphyrin compounds and sapphyrin compounds, as well as other polypyrrolic macrocycles, prepared using tripyrranes of Formula I as a precursor. These macrocycles are characterized by a tripyrrolic portion of the macrocyclic ring having substituents that cause the heterocycle to lack a plane of symmetry perpendicular to the plane of the macrocycle.

REFERENCES:
patent: 4935498 (1990-06-01), Sessler et al.
patent: 5041078 (1991-08-01), Matthews et al.
patent: 5051523 (1991-09-01), Peter et al.
patent: 5120411 (1992-06-01), Sessler et al.
patent: 5159065 (1992-10-01), Sessler et al.
patent: 5162509 (1992-11-01), Sessler et al.
patent: 5252720 (1993-10-01), Sessler et al.
patent: 5256399 (1993-10-01), Sessler et al.
patent: 5272142 (1993-12-01), Sessler et al.
patent: 5292414 (1994-03-01), Sessler et al.
patent: 5302714 (1994-04-01), Sessler et al.
patent: 5369101 (1994-11-01), Sessler et al.
patent: 5373093 (1994-12-01), Vallarino et al.
patent: 5432171 (1995-07-01), Sessler et al.
patent: 5439570 (1995-08-01), Sessler et al.
patent: 5451576 (1995-09-01), Sessler et al.
patent: 5457183 (1995-10-01), Sessler et al.
patent: 5457195 (1995-10-01), Sessler et al.
patent: 5475104 (1995-12-01), Sessler et al.
patent: 5504205 (1996-04-01), Sessler et al.
patent: 5525325 (1996-06-01), Sessler et al.
patent: 5530123 (1996-06-01), Sessler et al.
patent: 5543514 (1996-08-01), Sessler et al.
patent: 5559207 (1996-09-01), Sessler et al.
patent: 5565552 (1996-10-01), Magda et al.
patent: 5567687 (1996-10-01), Magda et al.
patent: 5569759 (1996-10-01), Sessler et al.
patent: 5580543 (1996-12-01), Sessler et al.
patent: 5583220 (1996-12-01), Sessler et al.
patent: 5587371 (1996-12-01), Sessler et al.
patent: 5587463 (1996-12-01), Sessler et al.
patent: 5587478 (1996-12-01), Sessler et al.
patent: 5591422 (1997-01-01), Hemmi et al.
patent: 5594136 (1997-01-01), Sessler et al.
patent: 5595726 (1997-01-01), Magda et al.
patent: 5599923 (1997-02-01), Sessler et al.
patent: 5599928 (1997-02-01), Hemmi et al.
patent: 5601802 (1997-02-01), Hemmi et al.
patent: 5607924 (1997-03-01), Magda et al.
patent: 5622946 (1997-04-01), Sessler et al.
patent: 5672490 (1997-09-01), Sessler et al.
patent: 5696240 (1997-12-01), Vallarino et al.
patent: 5714328 (1998-02-01), Magda et al.
patent: 5775339 (1998-07-01), Woodburn et al.
patent: 5776925 (1998-07-01), Young et al.
patent: 5798491 (1998-08-01), Magda et al.
patent: 5886173 (1999-03-01), Hemmi et al.
patent: 6072038 (2000-06-01), Sessler et al.
patent: WO 90/10633 (1990-09-01), None
patent: WO 94/09003 (1994-04-01), None
patent: WO 94/29316 (1994-12-01), None
patent: WO 95/10307 (1995-04-01), None
patent: WO 95/21845 (1995-08-01), None
patent: WO 96/09315 (1996-03-01), None
patent: WO 96/38461 (1996-12-01), None
patent: WO 96/40253 (1996-12-01), None
patent: WO 97/26915 (1997-07-01), None
patent: WO 97/35617 (1997-10-01), None
patent: WO 97/46262 (1997-12-01), None
patent: WO 98/07733 (1998-02-01), None
Sessler et al., “Texaphyrins: Synthesis and Applications,” Accounts of Chemical Research, vol. 27, No. 2, pp. 43-50 (1994).
Yougn et al., “Experimental Acute Cerebral Ischemia with Reperfusion: Evaluation with Gadolinium-Texaphyrin,” Investigative Radiology, vol. 31, No. 6, pp. 353-358 (1996).
Young et al., “Gadolinium(III) texaphyrin: A Tumor Selective Radiation Sensitizer that is Detectable by MRI,” Proc. Natl. Acad., vol. 93, pp. 6610-6615 (1996).
Young et al., “Imaging of Human Colon Cancer Xenograft with Gadolinium-Texaphyrin,” Investigative Radiology, vol. 31, No. 5, pp. 280-283 (1996).
PCT Notification of Transmittal of International Search Report, dated Dec. 13, 2001.

Affiliated with

Also associated with

Rating

Non-symmetric tripyrranes in the synthesis of novel macrocycles does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Non-symmetric tripyrranes in the synthesis of novel macrocycles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Non-symmetric tripyrranes in the synthesis of novel macrocycles will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3562659