Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Reexamination Certificate
2005-08-02
2005-08-02
Mosher, Mary E. (Department: 1648)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
C424S218100, C424S199100, C435S235100, C435S236000, C435S320100, C435S325000, C536S023720
Reexamination Certificate
active
06923969
ABSTRACT:
The invention relates to vaccines used in the eradication or control of pestivirus infections, particularly used in pigs or ruminants. The invention provides nucleic acid, pestivirus-like particles and a pestivirus vaccine, comprising the nucleic acid or particles, which is capable of eliciting a proper immune response without having the ability to spread throughout the vaccinated animal, thereby avoiding the negative consequences of viral spread. Preferably, the immunological response allows for serological discrimination between vaccinated animals and wild-type pestivirus infected animals.
REFERENCES:
patent: 5792462 (1998-08-01), Johnston et al.
patent: 6033886 (2000-03-01), Conzelmann
patent: 6168942 (2001-01-01), Cao et al.
patent: 6242259 (2001-06-01), Polo et al.
patent: 6555346 (2003-04-01), Kretzdorn et al.
patent: 0 389 034 (1990-12-01), None
patent: WO 95/34380 (1995-06-01), None
patent: WO 96/19498 (1996-06-01), None
patent: WO 96/25496 (1996-08-01), None
patent: WO 99/31257 (1998-12-01), None
patent: 99/28487 (1999-06-01), None
Moser et al (Journal of Virology 72(6): 5318-5322, Jun. 1998).
Meyers et al (Journal of Virology 70(12): 8606-8613, 1996).
Nettleton et al. British Veterinary Journal 151(6): 615-42, 1995 (abstract only cited).
Khromykh et al (Journal of Virology 72:7270-7279, Sep. 1998).
Lindenbach et al (Journal of Virology 71:9608-9617, Dec. 1997).
Khromykhh et al (Journal of Virology 71:1497-1505, Feb. 1997).
Meyers G. et al., “Classical Swine Fever Virus: Recovery of Infectious Viruses from cDNA Constructs and Generation of Recombinant Cytopathogenic Defective Interfering Particles,” Journal of Virology, vol. 70, No. 3, pp. 1588-1595, Mar. 1996, American Soc. for Microbiology US.
Moormann R. J. M. et al., “Infectious RNA Transcribed from an Engineered Full-Length cDNA Template of the Genome of a Pestivirus,” Journal of Virology, vol. 70, No. 2, pp. 763-770, Feb. 1996, American Soc. for Microbiology US.
Kuppermann H. et al., “Bovine Viral Diarrhea Virus: Characterization of a Cytopathogenic Defective Interfering Particle with Two Internal Delections,” Journal of Virology, vol. 70, No. 11, pp. 8175-8181, Nov. 1996, American Soc. for Microbiology US.
PCT International Preliminary Examination Report, PCT/NL00/00153, dated Jun. 15, 2001.
Peeters B. et al., “Biologically safe, non-transmissible pseudorabies virus vector vaccine protects pigs against both Aujeszky's disease and classical swine fever,” Journal of General Virology, vol. 78, pp. 3311-3115, 1997, GB.
van Rijn P.A. et al., “An experimental marker vaccine and accompanying serological diagnostic test both based on envelope glycoprotein E2 of classical swine fever virus (CSFV),” Vaccine 17, pp. 433-440, 1999, Deparment of Mammalian Virology, The Netherlands.
Moser, Christian, et al., “Detection of Antibodies Against Classical Swine Fever Virus in Swine Sera by Indirect ELISA Using Recombinant Envelope Glycoprotein E2,” Veterinary Microbiology 51, pp. 41-53, 1996.
van Rijn, P.A. et al., “Classical Swine Fever Virus (CSFV) Envelope Glycoprotein E2 Containing One Structural Antigenic Unit Protects Pigs from Lethal CSFV Challenge,” Journal of General Virology 77, pp. 2737-2745, 1996.
Hulst, M.M., et al., “Glycoprotein E1 of Hog Cholera Virus Expressed in Insect Cells Protects Swine from Hog Cholera,” Journal of Virology, pp. 5435-5442, Sep. 1993.
Ruggli, Nicolas, et al., “Baculovirus Expression and Affinity Purification of Protein E1 of Classical Swine Fever Virus Strain Alfort/187,” Virus Genes 10:2, pp. 115-126, 1995.
Hulst, Marcel M., et al., “Glycoprotein E2 of Classical Swine Fever Virus: Expression in Insect Cells and Identification as a Ribonuclease,” Virology 200, pp. 558-565, 1994.
Kweon, Chang-Hee, et al., “Expression of Envelope Protein (E2) of Bovine Viral Diarrhea Virus in Insect Cells,” J. Vet. Med. Sci. 59(5), pp. 415-419, 1997.
Reddy, J.R., et al., “Application of Recombinant Bovine Viral Proteins in the Diagnosis of Bovine Viral Diarrhea Infection in Cattle,” Veterinary Microbiology 51, pp. 119-133, 1997.
Petric, Martin, et al., “Baculovirus Expression of Pestivirus Non-Structural Proteins,” Journal of General Virology 73, pp. 1867-1871, 1992.
Chen, Liping, et al., “Coexpression of Cytochrome P4502A6 and Human NADPH-P450 Oxidoreductase in the Baculovirus System,” Drug Metabolism and Disposition 25:4, pp. 399-405, 1997.
Radford, Kathryn M., et al., “The Indirect Effects of Multiplicity of Infection on Baculovirus Expressed Proteins in Insect Cells: Secreted and Non-Secreted Products,” Cytotechnology 24, pp. 73-81, 1997.
Wu, Jianyong, et al., “Recombinant Protein Production in Insect Cell Cultures Infected with a Temperature-Sensitive Baculovirus,” Cytotechnology 9, pp. 141-147, 1992.
Nguyen, Binh, et al., “Fed-Batch Culture of Insect Cells: A Method to Increase the Yield of Recombinant Human Nerve Growth Factor (rhNGF) in the Baculovirus Expression System,” Journal of Biotechnology 31, pp. 205-217, 1993.
King, G., et al., “Assessment of Virus Production and Chloramphenicol Acetyl Transferase Expression of Insect Cells in Serum-Free and Serum-Supplemented Media Using a Temperature-Sensitive Baculovirus,” Biotechnology and Engineering 38, pp. 1091-1099, Nov. 1991.
Khromykh et al., trans-Complementation of Flavivirus RNA Polymerase Gene NS5 by Using Kuhjin Virus Replicon-Expressing BKH Cells, Journal of Virology, Sep. 1998, pp. 7270-7279, vol. 72, No. 9.
Wong et al., Low Multiplicity Infection of Insect Cells with a Recombinant Baculovirus: The Cell Yield Concept, Biotechnology and Bioengineering, vol. 49, pp. 659-666 (1996).
Hulst et al., Classical swine fever virus diagnostics and vaccine production in insect cells, Cytotechnology, vol. 20, pp. 271-279, 1996.
Moormann Robertus Jacobus Maria
Van Rijn Petrus Antonius
Widjojoatmodjo Myra N.
ID-Lelystad, Instituut voor Dierhouderij en Diergezondheid B.V.
Mosher Mary E.
TraskBritt
LandOfFree
Non-spreading pestivirus does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Non-spreading pestivirus, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Non-spreading pestivirus will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3445734