Non-specific immune system enhancement

Surgery – Blood drawn and replaced or treated and returned to body – Constituent removed from blood and remainder returned to body

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604 4, A61M 3700

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active

053838475

ABSTRACT:
The present invention pertains to a method for non-specifically enhancing the immune system response of a mammal to an antigen which comprises the steps of (a) withdrawing leukocyte containing material from the mammal, (b) treating the withdrawn leukocytes in a manner to alter the cells, and (c) returning the treated leukocytes to the mammal. In one embodiment, the method for non-specifically enhancing the immune system response of a mammal is carried out in conjunction with artificially contacting the mammal's immune system with an antigen for a suitable period of time to stimulate the immune system. In another embodiment, the mammal's immune system is naturally exposed to the antigen prior to the non-specific enhancement of the immune system. In yet another embodiment, the invention is directed at a method for preparing an autologous non-specific leukocyte adjuvant.

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patent: 4568328 (1986-02-01), King
patent: 4613322 (1986-09-01), Edelson
patent: 4683889 (1987-08-01), Edelson
patent: 4708715 (1987-11-01), Troutner et al.
patent: 4915683 (1990-04-01), Sieber

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